![]() ![]() Studies of methadone maintenance show initial efficacy following entrance to the program, and the medication remains effective in conjunction with other psychosocial forms of addiction treatment. Methadone is administered under the supervision of a physician. Typically, methadone is given daily in oral doses ranging from 30 to 100 mg or greater. Patients must meet admission requirements and must conform to clinic standards to participate in the program. Methadone maintenance is performed in programs that are in compliance with federal regulations. Methadone maintenance is a form of pharmacologic management of opiate addiction. Adjustments in dosage according to the patient's clinical state may be indicated.Ĭalculate barbiturate or benzodiazepine equivalence and give 50 percent of the original dosage taper (if actual dosage is known before detoxification). On day 1, give diazepam, 10 to 20 mg orally four times daily, and taper until the dosage is 5 to 10 mg orally on last day. Avoid giving the drug “as needed.” Adjustments in dosage according to the patient's clinical state may be indicated. On day 1, give diazepam (Valium), 10 to 20 mg orally four times daily, and taper until the dosage is 5 to 10 mg orally on last day. Hyperactivity, increased pain threshold, nystagmus, hyperreflexia, hypertension and tachycardia, eyelid retraction (stare), agitation and hyperarousal, dry and erythematous skin, violent and self-destructive behaviorsĪnxiety, depression, delusions, auditory and visual hallucinations, memory loss, irritable and angry mood and affect, suicidal thoughts ![]() Intense desire for drugs, muscle cramps, arthralgia, anxiety, nausea, vomiting, malaise Social withdrawal, psychomotor retardation, hypersomnia, hyperphagiaĭepression, anhedonia, suicidal thoughts and behavior, paranoid delusionsĭrug seeking, mydriasis, piloerection, diaphoresis, rhinorrhea, lacrimation, diarrhea, insomnia, elevated blood pressure and pulse (mild) Stimulants (cocaine, amphetamines and derivatives) Increased psychomotor activity, agitation, muscular weakness, tremulousness, hyperpyrexia, diaphoresis, delirium, convulsions, elevated blood pressure, pulse and temperature, tremor of eyelids, tongue and handsĪnxiety, depression, euphoria, incoherent thoughts, hostility, grandiosity, disorientation, tactile, auditory and visual hallucinations, suicidal thoughts Short-acting: 4 to 7 days Long-acting: 7 to 14 days Short-acting: 2 to 4 days Long-acting: 4 to 7 days Elevated blood pressure, pulse and temperature, hyperarousal, agitation, restlessness, cutaneous flushing, tremors, diaphoresis, dilated pupils, ataxia, clouding of consciousness, disorientationĪnxiety, panic, paranoid delusions, illusions, visual and auditory hallucinations (often derogatory and intimidating)īenzodiazepines and other sedative/hypnotics
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